Projects

This page highlights current AD-Genomics-Cardiff workstreams. Specific project names, datasets, and outputs can be added as they are ready to share publicly.

Integrative genetics workstream

Focus: Connecting Alzheimer’s disease risk loci to downstream biological mechanisms using genetic and multi-omics data.

Current activity: Placeholder summary for cohort integration, statistical analysis, and interpretation work led by the team.

Methods: GWAS, polygenic risk modelling, pathway analysis, and functional follow-up.

Evidence: - Placeholder project page or repository link - Placeholder report, preprint, or poster link - Placeholder dataset or methods resource

Sequencing and variant interpretation workstream

Focus: Using long-read sequencing and variant-calling workflows to improve resolution of Alzheimer’s disease-relevant genomic variation.

Current activity: Placeholder summary for pipeline development, benchmarking, quality control, and biological interpretation.

Methods: Long-read sequencing, variant calling, annotation, and comparative analyses.

Evidence: - Placeholder workflow or code repository link - Placeholder benchmark, manuscript, or presentation link - Placeholder documentation or resource link